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Home > Products >  Flunixin meglumin

Flunixin meglumin CAS NO.42461-84-7

  • Product Details

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  • Flunixin meglumin best offer
  • CAS 42461-84-7
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Quick Details

  • ProName: Flunixin meglumin
  • CasNo: 42461-84-7
  • Molecular Formula: C14H11F3N2O2
  • Appearance: White crystalline powder
  • Application: Veteinary pharmaceutical
  • DeliveryTime: 10days
  • PackAge: 25kg 10kg,5kgs
  • Port: Chinese main port
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: 98%
  • Storage: Dry and cool condition
  • Transportation: By air by sea or express
  • LimitNum: 1 Kilogram
  • Related Substances: 98%
  • Residue on Ignition: 0.3%
  • Heavy Metal: 0.3%
  • Valid Period: 3years

Superiority

Flunixin meglumin
Flunixin meglumine ;Flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. It is a potent inhibitor of the enzyme cyclooxygenase. It has demonstrated biological activity in the following areas:

 

  • Analgesia (loss of pain). Flunixin meglumine demonstrated potent analgesic activity in laboratory studies with mice, rats, and monkeys. Parenterally, flunixin meglumine showed anti-writhing activity in mice equal to pentazocine and was more potent than meperidine and codeine. In the rat yeast paw test, it was significantly more potent than pentazocine, meperidine, and codeine. In monkeys, flunixin meglumine produced analgesia comparable to a clinically effective dose of morphine. In the horse, it has been shown to be an effective treatment of pain associated with colic. In contrast to narcotic agents, its analgesic effects were not antagonized by naloxone, tolerance did not develop, and cross-tolerance to codeine did not occur. These results show that flunixin meglumine is an effective analgesic in animals, and drug dependence liability does not occur.

Details

Testing Items

Specifications

Results

Appearance

White to almost white, crystalline powder

Conforms

Solubility

Freely soluble in water and methanol, paractically insoluble in acetone

Conforms

Identification 1

Infrared absorption:197M;U ltraviolet absorption:197U

Conforms

Identification 2

Water: free soluble;Ethanol(96%):free soluble

Ethyl acetate: practically insoluble

Conforms

Melting Point

137~140℃

137.5~138.5

PH

5 %(W/V)water solution:7.0~9.0

8.2

Related Substances

2-chloropyridine-3carboxylic acid ≤0.2%

Undetected

2-methyl-3-(trifluoromethyl)aniline ≤0.2%

Undetected

Ethyl 2-chloropyridine-3-carboxylate ≤0.2%

Undetected

Ethyl 2-[[2-methyl-3-(trifluoromethyl)

Phenyl]amino]pyridine-3-carboxylate ≤0.2%

Undetected

Impurities

1.       Single impurity: not more than 0.2%

Conforms

2.       Unknown impurity: not more than 0.2%

Conforms

Total impurities(1~2): not more than 0.5%

Conforms

Specific optical rotation

-9.0°~ -12.0°

-10.3°

Solvent residue

Isopropanol: not more than 0.5%

Conforms

 

Ethanol: not more than 0.5%

Conforms

Bacterial endotoxins

Not more than 4.54 EU/mg

0.1 EU/mg

Loss on drying

≤0.5%

0.2%

Sulphated ash

≤0.1%

0.05%

Residue on ignition

≤0.2%

0.1%

Colour of solution

Clear,less coloured than reference solution y6,b.p.(Vet)

Conforms

Clarification

1.2g funixin meglumine/8.8g water

transparent

Explanation

Micronisarion 200±20um

Assay (HPLC)

99.0~101.0%

99.64%

Conclusion

 Comply with USP 37/EP7/BPV2012

 

Antimex Group, was founded in 2001,we are specializing in manufacturing & researching, warehouse & logistics of Active pharmaceutical Ingredients, pharmaceutical and chemical raw materials, Veterinary pharm APIs, food and feed additives,Chelate agent, Organo Silane,DCDFS(Dichlorodiphenylsilane) and water treatment chemicals Calcium Hipochlorite 65% and 70%. Some intermediate Including DA-6, NAA, IBA, IAA, 6-BA, cppu, compound Sodium Nitrophenolate, 1-MCP,Pharm intermediate and we can supply new products which custom synthesis required, Our markets cover all over the world,with the annual turnover of more than 10million dollars.

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