Flunixin meglumin CAS NO.42461-84-7
- FOB Price: USD: 110.00-110.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: D/P,T/T
- Available Specifications:
Pharmaceutical(1-50)Metric Ton
- Product Details
Keywords
- Flunixin meglumin best offer
- CAS 42461-84-7
- Flunixin meglumin manufactuer
Quick Details
- ProName: Flunixin meglumin
- CasNo: 42461-84-7
- Molecular Formula: C14H11F3N2O2
- Appearance: White crystalline powder
- Application: Veteinary pharmaceutical
- DeliveryTime: 10days
- PackAge: 25kg 10kg,5kgs
- Port: Chinese main port
- ProductionCapacity: 500 Kilogram/Week
- Purity: 98%
- Storage: Dry and cool condition
- Transportation: By air by sea or express
- LimitNum: 1 Kilogram
- Related Substances: 98%
- Residue on Ignition: 0.3%
- Heavy Metal: 0.3%
- Valid Period: 3years
Superiority
Flunixin meglumin
Flunixin meglumine ;Flunixin meglumine is a potent, non-narcotic, non-steroidal analgesic agent with anti-inflammatory and antipyretic activity. It is a potent inhibitor of the enzyme cyclooxygenase. It has demonstrated biological activity in the following areas:
- Analgesia (loss of pain). Flunixin meglumine demonstrated potent analgesic activity in laboratory studies with mice, rats, and monkeys. Parenterally, flunixin meglumine showed anti-writhing activity in mice equal to pentazocine and was more potent than meperidine and codeine. In the rat yeast paw test, it was significantly more potent than pentazocine, meperidine, and codeine. In monkeys, flunixin meglumine produced analgesia comparable to a clinically effective dose of morphine. In the horse, it has been shown to be an effective treatment of pain associated with colic. In contrast to narcotic agents, its analgesic effects were not antagonized by naloxone, tolerance did not develop, and cross-tolerance to codeine did not occur. These results show that flunixin meglumine is an effective analgesic in animals, and drug dependence liability does not occur.
Details
Testing Items |
Specifications |
Results |
Appearance |
White to almost white, crystalline powder |
Conforms |
Solubility |
Freely soluble in water and methanol, paractically insoluble in acetone |
Conforms |
Identification 1 |
Infrared absorption:197M;U ltraviolet absorption:197U |
Conforms |
Identification 2 |
Water: free soluble;Ethanol(96%):free soluble Ethyl acetate: practically insoluble |
Conforms |
Melting Point |
137~140℃ |
137.5~138.5 |
PH |
5 %(W/V)water solution:7.0~9.0 |
8.2 |
Related Substances |
2-chloropyridine-3carboxylic acid ≤0.2% |
Undetected |
2-methyl-3-(trifluoromethyl)aniline ≤0.2% |
Undetected |
|
Ethyl 2-chloropyridine-3-carboxylate ≤0.2% |
Undetected |
|
Ethyl 2-[[2-methyl-3-(trifluoromethyl) Phenyl]amino]pyridine-3-carboxylate ≤0.2% |
Undetected |
|
Impurities |
1. Single impurity: not more than 0.2% |
Conforms |
2. Unknown impurity: not more than 0.2% |
Conforms |
|
Total impurities(1~2): not more than 0.5% |
Conforms |
|
Specific optical rotation |
-9.0°~ -12.0° |
-10.3° |
Solvent residue |
Isopropanol: not more than 0.5% |
Conforms |
|
Ethanol: not more than 0.5% |
Conforms |
Bacterial endotoxins |
Not more than 4.54 EU/mg |
0.1 EU/mg |
Loss on drying |
≤0.5% |
0.2% |
Sulphated ash |
≤0.1% |
0.05% |
Residue on ignition |
≤0.2% |
0.1% |
Colour of solution |
Clear,less coloured than reference solution y6,b.p.(Vet) |
Conforms |
Clarification |
1.2g funixin meglumine/8.8g water |
transparent |
Explanation |
Micronisarion 200±20um |
|
Assay (HPLC) |
99.0~101.0% |
99.64% |
Conclusion |
Comply with USP 37/EP7/BPV2012 |
|
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