China (Mainland)
Assessedsupplier
OMEPRAZOLE CAS NO.119141-89-8
- Min.Order: 0 Metric Ton
- Payment Terms:
- Product Details
Keywords
- ZOLTUM
- (S)-OMEPRAZOLE
- 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE
Quick Details
- ProName: OMEPRAZOLE
- CasNo: 119141-89-8
- Molecular Formula: C17H19N3O3S
- Appearance: white powder
- Application: intermediates
- PackAge: aluminium bag
- Port: Shanghai,Qingdao
- ProductionCapacity: Metric Ton/Day
- Purity: 98% Min
- Storage: keep in dry and ventilated place
- Transportation: By sea/By air
- LimitNum: 0 Metric Ton
Superiority
Description: Omeprazole is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid.
Details
Synonym: Omeprazole, H 168-68, Losec, Prilosec, Zegerid
IUPAC/Chemical Name: 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
SMILES Code: O=S(C1=NC2=CC=C(OC)C=C2N1)CC3=NC=C(C)C(OC)=C3C
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Omeprazole Basic information |
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Product Name: |
Omeprazole |
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Synonyms: |
1h-benzimidazole,5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulf;2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine;5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazol;audazol;aulcer;belmazol;ceprandal;elgam |
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CAS: |
73590-58-6 |
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MF: |
C17H19N3O3S |
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MW: |
345.42 |
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EINECS: |
201-212-8 |
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Product Categories: |
Drug bulk;Active Pharmaceutical Ingredients;Omeprazole;Intermediates & Fine Chemicals;Pharmaceuticals;API's;ATPase;Metabolite Reference Standard;Isotopically Labeled Pharmaceutical Reference Standard;OSMITROL;Other APIs;Digestive System |
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Omeprazole Chemical Properties |
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mp |
156°C |
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storage temp. |
2-8°C |
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solubility |
H2O: 0.5 mg/mL |
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Merck |
6845 |
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Stability: |
Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark. |
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CAS DataBase Reference |
73590-58-6(CAS DataBase Reference) |
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Safety Information |
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Hazard Codes |
Xi,T,F |
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Risk Statements |
36/37/38-39/23/24/25-23/24/25-11 |
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Safety Statements |
26-36-37/39-45-36/37-16-7 |
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WGK Germany |
2 |
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RTECS |
DD9087000 |
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Hazardous Substances Data |
73590-58-6(Hazardous Substances Data) |
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Omeprazole Usage And Synthesis |
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Chemical Properties |
White Crystalline Solid |
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Usage |
Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative diuretic, sweetener, diagnostic aid A selective proton pump and CYP inhibitor Omeprazole Pellets are used in the treatment of Gastroesophageal reflux disease (GERD): A condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus) |
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Biological Activity |
H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell). |
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